Top 9 Best Strains for Depression

9 Best Strains for Depression

Depression is a common mental health condition that affects a large number of people worldwide. While traditional treatments such as medication and therapy can be beneficial, some people have found relief from depression through cannabis. 

Cannabis contains chemical compounds that influence how our bodies send messages to our brains. Some compounds work with the endocannabinoid system to promote physical and mental homeostasis. Other cannabis strains activate different molecular pathways, which usually produce medicinally effective results.

Here are nine of the best strains for depression that may relieve those suffering from this condition.


Harlequin has a CBD: THC ratio of 5:2. It has an energetic and uplifting effect, making it an excellent choice for people who are depressed. Some individuals favor this strain as it may help maintain a clear-headed and functional state of mind, which may be attributed to its nearly equal ratio of THC to CBD. The combination of these two cannabinoids may provide therapeutic benefits while limiting the psychoactive effects of THC, making it a suitable option for those who want to experience the potential benefits of cannabis without feeling overly intoxicated.

Blue dream

Blue Dream is a Sativa-dominant hybrid strain known for its uplifting and euphoric effects. It has a medium to high THC content and is popular among those seeking relief from depression, stress, and anxiety symptoms. The high THC content of the strain has been linked to its mood-boosting effects, and its Sativa dominant genetics make it an ideal strain for depression for prime-time use.

Northern Lights

This is an Indica-dominant cannabis strain, which has a strong THC content. It is known for producing a relaxing and sedative high, making it an excellent choice for people suffering from depression or anxiety. The mellow vibes of the Northern Lights are said to help some people sleep better, which is an added advantage because insomnia has been linked to depression.

Durban Poison

Durban Poison, another landrace strain, is a pure sativa known for producing powerfully psychoactive—almost psychedelic—effects. It has a THC content of 26% and a CBD content of 1%. Terpinolene and humulene are its primary and secondary terpenes. If depression is preventing you from pursuing creative efforts or diminishing your energy reserves, Durban Poison is a relieving strain for depression that can help you.


MediHaze is a CBD-rich strain that is frequently classified as a Sativa hybrid. With a 1:1 or higher ratio of CBD to THC, this cannabis strain is an excellent choice for those suffering from depression and not wanting the intoxicating effects of THC. Using this strain during the daylight is safe, giving you a jolting boost of mental energy. CBD can increase feel-good serotonin levels in the brain more quickly and effectively than pharmacological antidepressant medications.

Cherry Punch

Cherry Punch is a hybrid cannabis strain recognized for its potent and therapeutic properties thanks to its high concentration of beneficial terpenes. The strain is infused with terpenes, including myrcene, humulene, and linalool, which may provide various therapeutic benefits. The strain is a cross between AK 47 and Purple Punch, creating a unique cherry vanilla flavor profile that users may find enjoyable. Some users have reported experiencing cheerful effects when using Cherry Punch, which may be attributed to its well-balanced blend of cannabinoids and terpenes. Overall, Cherry Punch may be a suitable option for those who want to experience the potential benefits of cannabis while enjoying a pleasant and flavorful experience

Super Sour Diesel

Super Sour Diesel is a popular morning cannabis strain for a reason. This strain is known for producing high levels of mood-lifting terpenes such as beta-caryophyllene, limonene, and bisabolol. Beta-caryophyllene (BCP), which has been studied in preclinical studies, has been discovered to have antidepressant qualities. BCP is a pungent-smelling terpene found in lemon balm and black pepper. It produces an energetic and creative high, which may help people suffering from depression by improving their mood and confidence.


This CBD-rich cannabis strain is popular among those looking to alleviate depression symptoms. A combination of relaxing myrcene and energizing pinene counteracts myrcene’s sedative effects, while low levels of THC help to alleviate the anxiety that frequently accompanies depression. This strain for depression has a healthy THC-to-CBD ratio. Cannatonic, a hybrid of Indica and Sativa, uplifts mood and treats depression.


Cinex is a THC-rich strain that can boost creativity and help people perform tasks that depression might otherwise prevent. Cinex’s limonene, which has a citrus scent, can also enliven the senses and improve mood.


Many people use cannabis to alleviate depression symptoms. It is important to remember that cannabis use can have a negative impact on mental health, including worsening symptoms of depression, anxiety, and other mental health conditions. Itis always a good idea to consult a cannabis doctor and get a medical marijuana card before using or consuming it in any way. Suppose you are experiencing depression or other mental health issues. In that case, it is critical that you seek the advice of a medical professional who can help you find appropriate treatments and resources. Online Medical Marijuana Card is available in states such as West Virginia.


Even though cannabis strains can potentially alleviate depression, it is important to seek medical advice before using strains as a treatment for depression. Furthermore, people should start with a low dosage and gradually increase it to find the right strain and dosage. The above-said strains for depression could be a good starting point for people interested in using a natural remedy to alleviate their depression symptoms.

Leave a Reply

Your email address will not be published. Required fields are marked *